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Likewise, TGF-β1 suppressed the expression of GCLC (no effect on GCLM) and lowered GSH levels in rat hepatic stellate cells (HSCs), which facilitated fibrogenesis (Fu et al., 2008)

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Severe COVID-19 induces extensive pulmonary inflammation, triggering a macrophage activation syndrome (MAS)-like event with proinflammatory cytokines, macrophage and lymphocyte recruitment, and subsequent endothelial damage [15]

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