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In the liver, hepatocytes lining the biliary canalicular surface express P-gp ( Reference Thiebaut, Tsuruo and Hamada 27 ) and secrete substrates, including vitamin E and its metabolites ( Reference Mustacich, Shields and Horton 63 ) , into the bile

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The Fisher’s exact test was used when the genotypic and allelic frequencies were less than 5%